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Genetic variation that predicts platinum sensitivity reveals the role of miR-193b* in chemotherapeutic susceptibility

Platinum agents are the backbone of cancer chemotherapy. Recently we identified and replicated the role of a single nucleotide polymorphism (SNP, rs1649942) in predicting platinum sensitivity both in vitro and in vivo. Using the CEU samples from the International HapMap Project, we found the same SN...

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Detalhes bibliográficos
Main Authors: Ziliak, Dana, Gamazon, Eric R., LaCroix, Bonnie, Im, Hae Kyung, Wen, Yujia, Huang, Rong Stephanie
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3438340/
https://ncbi.nlm.nih.gov/pubmed/22752226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-12-0221
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