MSH2-Dependent Germinal CTG Repeat Expansions Are Produced Continuously in Spermatogonia from DM1 Transgenic Mice

Myotonic dystrophy type 1 is a neuromuscular affection associated with the expansion of an unstable CTG repeat in the DM protein kinase gene. The disease is characterized by somatic tissue-specific mosaicism and very high intergenerational instability with a strong bias towards expansions. We used t...

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Podrobná bibliografie

Vydáno v:	Mol Cell Biol
Hlavní autoři:	Savouret, Cédric, Garcia-Cordier, Corinne, Megret, Jérôme, te Riele, Hein, Junien, Claudine, Gourdon, Geneviève
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Taylor & Francis 2004
Témata:	DNA Dynamics and Chromosome Structure
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC343816/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14701736/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.2.629-637.2004
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