Nuclear Reorganization of Mammalian DNA Synthesis Prior to Cell Cycle Exit

In primary mammalian cells, DNA replication initiates in a small number of perinucleolar, lamin A/C-associated foci. During S-phase progression in proliferating cells, replication foci distribute to hundreds of sites throughout the nucleus. In contrast, we find that the limited perinucleolar replica...

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Detalhes bibliográficos
Main Authors: Barbie, David A., Kudlow, Brian A., Frock, Richard, Zhao, Jiyong, Johnson, Brett R., Dyson, Nicholas, Harlow, Ed, Kennedy, Brian K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
DNA Dynamics and Chromosome Structure
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC343811/
https://ncbi.nlm.nih.gov/pubmed/14701733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.2.595-607.2004
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