Chk2 Phosphorylation of BRCA1 Regulates DNA Double-Strand Break Repair

The pathway determining malignant cellular transformation, which depends upon mutation of the BRCA1 tumor suppressor gene, is poorly defined. A growing body of evidence suggests that promotion of DNA double-strand break repair by homologous recombination (HR) may be the means by which BRCA1 maintain...

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Detalles Bibliográficos

Publicado en:	Mol Cell Biol
Autores principales:	Zhang, Junran, Willers, Henning, Feng, Zhihui, Ghosh, Jagadish C., Kim, Sang, Weaver, David T., Chung, Jay H., Powell, Simon N., Xia, Fen
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Taylor & Francis 2004
Materias:	DNA Dynamics and Chromosome Structure
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC343805/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14701743/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.2.708-718.2004
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