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Distinct Domains in the SHP-2 Phosphatase Differentially Regulate Epidermal Growth Factor Receptor/NF-κB Activation through Gab1 in Glioblastoma Cells

The transcription factor nuclear factor κB (NF-κB) plays an important role in inflammation and cancer, is activated by a variety of stimuli including tumor necrosis factor alpha, interleukin-1, UV irradiation, and viruses, as well as receptor tyrosine kinases, such as epidermal growth factor recepto...

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Detalhes bibliográficos
Main Authors: Kapoor, Gurpreet S., Zhan, Yi, Johnson, Gibbes R., O'Rourke, Donald M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC343802/
https://ncbi.nlm.nih.gov/pubmed/14701753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.2.823-836.2004
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