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HOXA5-Induced Apoptosis in Breast Cancer Cells Is Mediated by Caspases 2 and 8

HOXA5 is a transcriptional factor whose expression is lost in more than 60% of breast carcinomas. Our previous work demonstrated that the overexpression of HOXA5 in MCF7 cells resulted in cell death through a p53-dependent apoptotic pathway. To determine whether p53-independent apoptotic pathways ar...

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Bibliografski detalji
Glavni autori: Chen, Hexin, Chung, Seung, Sukumar, Saraswati
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2004
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC343791/
https://ncbi.nlm.nih.gov/pubmed/14701762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.2.924-935.2004
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