An RNA virus hijacks an incognito function of a DNA repair enzyme

A previously described mammalian cell activity, called VPg unlinkase, specifically cleaves a unique protein–RNA covalent linkage generated during the viral genomic RNA replication steps of a picornavirus infection. For over three decades, the identity of this cellular activity and its normal role in...

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Detalhes bibliográficos
Main Authors: Virgen-Slane, Richard, Rozovics, Janet M., Fitzgerald, Kerry D., Ngo, Tuan, Chou, Wayne, van der Heden van Noort, Gerbrand J., Filippov, Dmitri V., Gershon, Paul D., Semler, Bert L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3437895/
https://ncbi.nlm.nih.gov/pubmed/22908287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1208096109
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