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Axon guidance in the developing ocular motor system and Duane retraction syndrome depends on Semaphorin signaling via alpha2-chimaerin

Eye movements depend on correct patterns of connectivity between cranial motor axons and the extraocular muscles. Despite the clinical importance of the ocular motor system, little is known of the molecular mechanisms underlying its development. We have recently shown that mutations in the Chimaerin...

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Detalhes bibliográficos
Main Authors: Ferrario, Juan E., Baskaran, Pranetha, Clark, Christopher, Hendry, Aenea, Lerner, Oleg, Hintze, Mark, Allen, James, Chilton, John K., Guthrie, Sarah
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3437829/
https://ncbi.nlm.nih.gov/pubmed/22912401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1116481109
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