Microbial Exposure During Early Life Has Persistent Effects on Natural Killer T Cell Function

Exposure to microbes during early childhood is associated with protection from immune-mediated diseases such as inflammatory bowel disease (IBD) and asthma. Here, we show that in germ-free (GF) mice, invariant natural killer T (iNKT) cells accumulate in the colonic lamina propria and lung, resulting...

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Detalhes bibliográficos
Main Authors: Olszak, Torsten, An, Dingding, Zeissig, Sebastian, Vera, Miguel Pinilla, Richter, Julia, Franke, Andre, Glickman, Jonathan N., Siebert, Reiner, Baron, Rebecca M., Kasper, Dennis L., Blumberg, Richard S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3437652/
https://ncbi.nlm.nih.gov/pubmed/22442383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1219328
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