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bis-Pyridinium Cyclophanes: Novel Ligands with High Affinity for the Blood-Brain Barrier Choline Transporter
A series of bis-pyridinium cyclophane analogs designed as conformationally-restricted bis-quaternary ammonium compounds were evaluated for their affinity for the blood-brain barrier (BBB) choline transporter. All the cyclophanes investigated exhibited high affinity compared to choline. Of these comp...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3437650/ https://ncbi.nlm.nih.gov/pubmed/18793853 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2008.08.099 |
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