Human regulatory T cells induce T-lymphocyte senescence

Regulatory T (Treg) cells have broad suppressive activity on host immunity, but the fate and function of suppressed responder T cells remains largely unknown. In the present study, we report that human Treg cells can induce senescence in responder naive and effector T cells in vitro and in vivo. Sen...

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Main Authors: Ye, Jian, Huang, Xingxu, Hsueh, Eddy C., Zhang, Qunyuan, Ma, Chunling, Zhang, Yanping, Varvares, Mark A., Hoft, Daniel F., Peng, Guangyong
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2012
Assuntos:
Immunobiology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3437594/
https://ncbi.nlm.nih.gov/pubmed/22723548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-03-416040
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