Lentiviral Vectors Displaying Modified Measles Virus gp Overcome Pre-existing Immunity in In Vivo-like Transduction of Human T and B Cells

Gene transfer into quiescent T and B cells is important for gene therapy and immunotherapy approaches. Previously, we generated lentiviral vectors (LVs) pseudotyped with Edmonston (Ed) measles virus (MV) hemagglutinin (H) and fusion (F) glycoproteins (H/F-LVs), which allowed efficient transduction o...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Lévy, Camille, Amirache, Fouzia, Costa, Caroline, Frecha, Cecilia, Muller, Claude P, Kweder, Hasan, Buckland, Robin, Cosset, François-Loïc, Verhoeyen, Els
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2012
Sujets:
Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3437580/
https://ncbi.nlm.nih.gov/pubmed/22617109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2012.96
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