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Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy
Hypoxia-inducible factors (HIFs) mediate adaptive physiological responses to hypoxia. In human cancers that are accessible for O(2) electrode measurements, intratumoral hypoxia is common and is associated with increased risk of mortality. HIF activity in regions of intratumoral hypoxia mediates angi...
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
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2012
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| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3437546/ https://ncbi.nlm.nih.gov/pubmed/22398146 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2012.01.005 |
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