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The problems of eukaryotic and prokaryotic DNA packaging and in vivo conformation posed by superhelix density heterogeneity

Systems for gel electrophoresis in the presence of one of the intercalative unwinding ligands, ethidium or chloroquine, have been developed which permit the resolution of highly supercoiled closed circular DNA molecules differing by unit values of the topological winding number, α. All native closed...

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Bibliografische gegevens
Hoofdauteurs: Shure, Mavis, Pulleyblank, David E., Vinograd, Jerome
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1977
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC343749/
https://ncbi.nlm.nih.gov/pubmed/197488
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