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The problems of eukaryotic and prokaryotic DNA packaging and in vivo conformation posed by superhelix density heterogeneity

Systems for gel electrophoresis in the presence of one of the intercalative unwinding ligands, ethidium or chloroquine, have been developed which permit the resolution of highly supercoiled closed circular DNA molecules differing by unit values of the topological winding number, α. All native closed...

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Publicat a:Nucleic Acids Res
Autors principals: Shure, Mavis, Pulleyblank, David E., Vinograd, Jerome
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 1977
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC343749/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/197488/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/4.5.1183
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