The TNF-family cytokine TL1A drives IL-13-dependent small intestinal inflammation

The TNF family cytokine TL1A (TNFSF15) costimulates T cells through its receptor DR3 (TNFRSF25) and is required for autoimmune pathology driven by diverse T cell subsets. TL1A has been linked to human inflammatory bowel disease (IBD), but its pathogenic role is not known. We generated transgenic mic...

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Autori principali: Meylan, Françoise, Song, Yun-Jeong, Fuss, Ivan, Villarreal, Sarah, Kahle, Erin, Malm, Ian-James, Acharya, Krishika, Ramos, Haydee L., Lo, Larry, Mentink-Kane, Margaret M., Wynn, Thomas A., Migone, Thi-Sau, Strober, Warren, Siegel, Richard M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3437258/
https://ncbi.nlm.nih.gov/pubmed/20980995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2010.67
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