Nilotinib protects the murine liver from ischemia/reperfusion injury

BACKGROUND & AIM: The mitogen-activated protein kinases (MAPKs) c-Jun N-terminal kinase (JNK) and p38 mediate liver ischemia/reperfusion (I/R) injury via cell death and inflammatory cytokine expression, respectively. Nilotinib is an orally available receptor tyrosine kinase inhibitor used for ch...

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Autors principals: Ocuin, Lee M., Zeng, Shan, Cavnar, Michael J., Sorenson, Eric C., Bamboat, Zubin M., Greer, Jonathan B., Kim, Teresa S., Popow, Rachel, DeMatteo, Ronald P.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3437237/
https://ncbi.nlm.nih.gov/pubmed/22641092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2012.05.012
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