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Toll-like receptor 9 inhibition confers protection from liver ischemia-reperfusion injury()

Endogenous ligands such as high-mobility group box 1 (HMGB1) and nucleic acids are released by dying cells and bind Toll-like receptors (TLRs). Because TLR9 sits at the interface of microbial and sterile inflammation by detecting both bacterial and endogenous DNA, we investigated its role in a model...

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Auteurs principaux: Bamboat, Zubin M., Balachandran, Vinod P., Ocuin, Lee M., Obaid, Hebroon, Plitas, George, DeMatteo, Ronald P.
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164814/
https://ncbi.nlm.nih.gov/pubmed/19902481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.23365
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