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Loop Residues and Catalysis in OMP Synthase()
Residue-to-alanine mutations and a two amino acid deletant have been made in the highly conserved catalytic loop (residues 100-109) of Salmonella typhimurium OMP synthase (orotate phosphoribosyltransferase, E.C. 2.4.2.10). As described previously, the K103A mutant enzyme showed a 10(4)-fold decrease...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3436960/ https://ncbi.nlm.nih.gov/pubmed/22531099 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi300082s |
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