Trefoil factor 2 negatively regulates Type 1 immunity against Toxoplasma gondii

Interleukin 12 (IL-12)-mediated Type 1 inflammation confers host-protection against the parasitic protozoan Toxoplasma gondii. However, production of interferon gamma (IFN-γ), another Type 1 inflammatory cytokine, also drives lethality from excessive injury to the intestinal epithelium. As mechanism...

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Detalhes bibliográficos
Main Authors: McBerry, Cortez, Egan, Charlotte E., Rani, Reena, Yang, Yanfen, Wu, David, Boespflug, Nicholas, Boon, Louis, Butcher, Barbara, Mirpuri, Julie, Hogan, Simon P., Denkers, Eric Y., Aliberti, Julio, Herbert, De’Broski R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436937/
https://ncbi.nlm.nih.gov/pubmed/22896633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1103374
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