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Identifying functional modules in interaction networks through overlapping Markov clustering

Motivation: In recent years, Markov clustering (MCL) has emerged as an effective algorithm for clustering biological networks—for instance clustering protein–protein interaction (PPI) networks to identify functional modules. However, a limitation of MCL and its variants (e.g. regularized MCL) is tha...

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Bibliographic Details
Main Authors: Shih, Yu-Keng, Parthasarathy, Srinivasan
Format: Artigo
Language:Inglês
Published: Oxford University Press 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436797/
https://ncbi.nlm.nih.gov/pubmed/22962469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bts370
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