Biodistribution and elimination kinetics of systemic Stx2 by the Stx2A and Stx2B subunit-specific human monoclonal antibodies in mice

BACKGROUND: Hemolytic uremic syndrome (HUS) leading to acute kidney failure, is a condition linked to the production of primarily Shiga toxin 2 (Stx2) by some E. coli serotypes. We have previously shown that Stx2 A subunit-specific human monoclonal antibody (HuMAb) 5C12, and B subunit-specific HuMAb...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Sheoran, Abhineet, Jeong, Kwang-il, Mukherjee, Jean, Wiffin, Anthony, Singh, Pradeep, Tzipori, Saul
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2012
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436740/
https://ncbi.nlm.nih.gov/pubmed/22655967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2172-13-27
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky