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Ataxin-3 Regulates Aggresome Formation of Copper-Zinc Superoxide Dismutase (SOD1) by Editing K63-linked Polyubiquitin Chains

Polyubiquitination of misfolded proteins, especially K63-linked polyubiquitination, is thought to be associated with the formation of inclusion bodies. However, it is not well explored whether appropriate editing of the different types of ubiquitin linkages by deubiquitinating enzymes (DUBs) affects...

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Bibliografske podrobnosti
Main Authors: Wang, Hongfeng, Ying, Zheng, Wang, Guanghui
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436588/
https://ncbi.nlm.nih.gov/pubmed/22761419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.299990
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