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Ataxin-3 Regulates Aggresome Formation of Copper-Zinc Superoxide Dismutase (SOD1) by Editing K63-linked Polyubiquitin Chains

Polyubiquitination of misfolded proteins, especially K63-linked polyubiquitination, is thought to be associated with the formation of inclusion bodies. However, it is not well explored whether appropriate editing of the different types of ubiquitin linkages by deubiquitinating enzymes (DUBs) affects...

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Autors principals: Wang, Hongfeng, Ying, Zheng, Wang, Guanghui
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436588/
https://ncbi.nlm.nih.gov/pubmed/22761419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.299990
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