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Tumorigenesis of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx), but not enhancing effects of concomitant high-fat diet, on lung carcinogenesis in female A/J mice

It has been reported that 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx) induces liver tumors and to a lesser extent lung lesions, lymphomas and leukemias in CDF(1) mice. Since a number of case control studies have pointed to a positive association between fat consumption and lung cancer, we...

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Autors principals: TAKEUCHI, HIJIRI, SAOO, KOUSUKE, YAMAKAWA, KEIKO, MATSUDA, YOKO, YOKOHIRA, MASANAO, ZENG, YU, KUNO, TOTSHIYA, TOTSUKA, YUKARI, TAKAHASHI, MAMI, WAKABAYASHI, KEIJI, IMAIDA, KATSUMI
Format: Artigo
Idioma:Inglês
Publicat: D.A. Spandidos 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436480/
https://ncbi.nlm.nih.gov/pubmed/22966271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol_00000025
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