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Multispecies model of cell lineages and feedback control in solid tumors

We develop a multispecies continuum model to simulate the spatiotemporal dynamics of cell lineages in solid tumors. The model accounts for protein signaling factors produced by cells in lineages, and nutrients supplied by the microenvironment. Together, these regulate the rates of proliferation, sel...

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Bibliographic Details
Main Authors: Youssefpour, H., Li, X., Lander, A.D., Lowengrub, J.S.
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436435/
https://ncbi.nlm.nih.gov/pubmed/22554945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtbi.2012.02.030
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