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Lipid Rafts Alter the Stability and Activity of the Cholera Toxin A1 Subunit
Cholera toxin (CT) travels from the cell surface to the endoplasmic reticulum (ER) as an AB holotoxin. ER-specific conditions then promote the dissociation of the catalytic CTA1 subunit from the rest of the toxin. CTA1 is held in a stable conformation by its assembly in the CT holotoxin, but the dis...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Biochemistry and Molecular Biology
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3436369/ https://ncbi.nlm.nih.gov/pubmed/22787142 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.385575 |
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