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Biochemical Analysis of Hypermutation by the Deoxycytidine Deaminase APOBEC3A

APOBEC3A belongs to a family of single-stranded DNA (ssDNA) DNA cytosine deaminases that are known for restriction of HIV through deamination-induced mutational inactivation, e.g. APOBEC3G, or initiation of somatic hypermutation and class switch recombination (activation-induced cytidine deaminase)....

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Detalhes bibliográficos
Main Authors: Love, Robin P., Xu, Huixin, Chelico, Linda
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436324/
https://ncbi.nlm.nih.gov/pubmed/22822074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.393181
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