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Biochemical Analysis of Hypermutation by the Deoxycytidine Deaminase APOBEC3A
APOBEC3A belongs to a family of single-stranded DNA (ssDNA) DNA cytosine deaminases that are known for restriction of HIV through deamination-induced mutational inactivation, e.g. APOBEC3G, or initiation of somatic hypermutation and class switch recombination (activation-induced cytidine deaminase)....
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Main Authors: | , , |
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Formáid: | Artigo |
Teanga: | Inglês |
Foilsithe: |
American Society for Biochemistry and Molecular Biology
2012
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Ábhair: | |
Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3436324/ https://ncbi.nlm.nih.gov/pubmed/22822074 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.393181 |
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