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Analysis of Transient Receptor Potential Ankyrin 1 (TRPA1) in Frogs and Lizards Illuminates Both Nociceptive Heat and Chemical Sensitivities and Coexpression with TRP Vanilloid 1 (TRPV1) in Ancestral Vertebrates

Transient receptor potential ankyrin 1 (TRPA1) and TRP vanilloid 1 (V1) perceive noxious temperatures and chemical stimuli and are involved in pain sensation in mammals. Thus, these two channels provide a model for understanding how different genes with similar biological roles may influence the fun...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Saito, Shigeru, Nakatsuka, Kazumasa, Takahashi, Kenji, Fukuta, Naomi, Imagawa, Toshiaki, Ohta, Toshio, Tominaga, Makoto
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436318/
https://ncbi.nlm.nih.gov/pubmed/22791718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.362194
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