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Thioredoxin Reductase Linked to Cytoskeleton by Focal Adhesion Kinase Reverses Actin S-Nitrosylation and Restores Neutrophil β(2) Integrin Function
The investigation goal was to identify mechanisms for reversal of actin S-nitrosylation in neutrophils after exposure to high oxygen partial pressures. Prior work has shown that hyperoxia causes S-nitrosylated actin (SNO-actin) formation, which mediates β(2) integrin dysfunction, and these changes c...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3436286/ https://ncbi.nlm.nih.gov/pubmed/22778269 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.355875 |
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