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Thioredoxin Reductase Linked to Cytoskeleton by Focal Adhesion Kinase Reverses Actin S-Nitrosylation and Restores Neutrophil β(2) Integrin Function

The investigation goal was to identify mechanisms for reversal of actin S-nitrosylation in neutrophils after exposure to high oxygen partial pressures. Prior work has shown that hyperoxia causes S-nitrosylated actin (SNO-actin) formation, which mediates β(2) integrin dysfunction, and these changes c...

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Bibliografische gegevens
Hoofdauteurs: Thom, Stephen R., Bhopale, Veena M., Milovanova, Tatyana N., Yang, Ming, Bogush, Marina
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436286/
https://ncbi.nlm.nih.gov/pubmed/22778269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.355875
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