A novel, highly sensitive and rapid allele-specific loop-mediated amplification assay for the detection of the JAK2V617F mutation in chronic myeloproliferative neoplasms

BACKGROUND: The identification of the JAK2V617F mutation is mandatory in the diagnostic work-up of Philadelphia chromosome-negative myeloproliferative neoplasms. Several molecular techniques to detect this mutation are currently available, but each of them has some limits. DESIGN AND METHODS: We set...

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Main Authors: Minnucci, Giulia, Amicarelli, Giulia, Salmoiraghi, Silvia, Spinelli, Orietta, Guinea Montalvo, Marie Lorena, Giussani, Ursula, Adlerstein, Daniel, Rambaldi, Alessandro
Format: Artigo
Sprog:Inglês
Udgivet: Ferrata Storti Foundation 2012
Fag:
Original Articles and Brief Reports
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436241/
https://ncbi.nlm.nih.gov/pubmed/22315499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2011.056184
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