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Prognostic significance of ASXL1, JAK2V617F mutations and JAK2V617F allele burden in Philadelphia-negative myeloproliferative neoplasms

BACKGROUND: Despite insights into the genetic basis of Philadelphia-negative myeloproliferative neoplasms (Ph-negative MPNs), a significant proportion of essential thrombocythemia (ET) and primary myelofibrosis (PMF) patients present with no known MPN disease alleles. There were no previous studies...

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Publicado en:J Blood Med
Main Authors: Yonal-Hindilerden, Ipek, Daglar-Aday, Aynur, Akadam-Teker, Basak, Yilmaz, Ceylan, Nalcaci, Meliha, Yavuz, Akif Selim, Sargin, Deniz
Formato: Artigo
Idioma:Inglês
Publicado: Dove Medical Press 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4459634/
https://ncbi.nlm.nih.gov/pubmed/26082670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JBM.S78826
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