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Pontin is essential for murine hematopoietic stem cell survival

Pontin is a highly conserved DNA helicase/ATPase which is a component of several macromolecular complexes with functions that include DNA repair, telomere maintenance and tumor suppression. While Pontin is known to be essential in yeast, fruit flies and frogs, its physiological role in mammalian org...

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Detalhes bibliográficos
Main Authors: Bereshchenko, Oxana, Mancini, Elena, Luciani, Luisa, Gambardella, Adriana, Riccardi, Carlo, Nerlov, Claus
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436228/
https://ncbi.nlm.nih.gov/pubmed/22371176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2011.060251
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