Protein Disulfide Isomerase Is Required for Platelet-derived Growth Factor-induced Vascular Smooth Muscle Cell Migration, Nox1 NADPH Oxidase Expression, and RhoGTPase Activation

Vascular Smooth Muscle Cell (VSMC) migration into vessel neointima is a therapeutic target for atherosclerosis and postinjury restenosis. Nox1 NADPH oxidase-derived oxidants synergize with growth factors to support VSMC migration. We previously described the interaction between NADPH oxidases and th...

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Autori principali: Pescatore, Luciana A., Bonatto, Diego, Forti, Fábio L., Sadok, Amine, Kovacic, Hervé, Laurindo, Francisco R. M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2012
Soggetti:
Molecular Bases of Disease
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436193/
https://ncbi.nlm.nih.gov/pubmed/22773830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.394551
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