Caricamento...

Identification of Akt-independent Regulation of Hepatic Lipogenesis by Mammalian Target of Rapamycin (mTOR) Complex 2

Mammalian target of rapamycin complex 2 (mTORC2) is a key activator of protein kinases that act downstream of insulin and growth factor signaling. Here we report that mice lacking the essential mTORC2 component rictor in liver (Lrictor(KO)) are unable to respond normally to insulin. In response to i...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Yuan, Minsheng, Pino, Elizabeth, Wu, Lianfeng, Kacergis, Michael, Soukas, Alexander A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2012
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436168/
https://ncbi.nlm.nih.gov/pubmed/22773877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.386854
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !