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An inwardly rectifying K(+) channel is required for patterning

Mutations that disrupt function of the human inwardly rectifying potassium channel KIR2.1 are associated with the craniofacial and digital defects of Andersen-Tawil Syndrome, but the contribution of Kir channels to development is undefined. Deletion of mouse Kir2.1 also causes cleft palate and digit...

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Autors principals: Dahal, Giri Raj, Rawson, Joel, Gassaway, Brandon, Kwok, Benjamin, Tong, Ying, Ptáček, Louis J., Bates, Emily
Format: Artigo
Idioma:Inglês
Publicat: Company of Biologists 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436115/
https://ncbi.nlm.nih.gov/pubmed/22949619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.078592
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