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miR-92b regulates Mef2 levels through a negative-feedback circuit during Drosophila muscle development

Mef2 is the key transcription factor for muscle development and differentiation in Drosophila. It activates hundreds of downstream target genes, including itself. Precise control of Mef2 levels is essential for muscle development as different Mef2 protein levels activate distinct sets of muscle gene...

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Detalhes bibliográficos
Main Authors: Chen, Zhimin, Liang, Shanshan, Zhao, Ying, Han, Zhe
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436111/
https://ncbi.nlm.nih.gov/pubmed/22899845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.082719
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