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Kinetic analysis of thermal stability of human low density lipoproteins: a model for LDL fusion in atherogenesis

Fusion of modified LDL in the arterial wall promotes atherogenesis. Earlier we showed that thermal denaturation mimics LDL remodeling and fusion, and revealed kinetic origin of LDL stability. Here we report the first quantitative analysis of LDL thermal stability. Turbidity data show sigmoidal kinet...

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Main Authors: Lu, Mengxiao, Gantz, Donald L., Herscovitz, Haya, Gursky, Olga
格式: Artigo
語言:Inglês
出版: The American Society for Biochemistry and Molecular Biology 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3435550/
https://ncbi.nlm.nih.gov/pubmed/22855737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M029629
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