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Kinetic analysis of thermal stability of human low density lipoproteins: a model for LDL fusion in atherogenesis

Fusion of modified LDL in the arterial wall promotes atherogenesis. Earlier we showed that thermal denaturation mimics LDL remodeling and fusion, and revealed kinetic origin of LDL stability. Here we report the first quantitative analysis of LDL thermal stability. Turbidity data show sigmoidal kinet...

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Detalhes bibliográficos
Main Authors: Lu, Mengxiao, Gantz, Donald L., Herscovitz, Haya, Gursky, Olga
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3435550/
https://ncbi.nlm.nih.gov/pubmed/22855737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M029629
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