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EXPRESSION OF SCLEROSTIN IN THE DEVELOPING ZEBRAFISH (DANIO) BRAIN AND SKELETON

Sclerostin is a highly conserved, secreted, cystine-knot protein which regulates osteoblast function. Humans with mutations in the sclerostin gene (SOST), manifest increased axial and appendicular skeletal bone density with attendant complications. In adult bone, sclerostin is expressed in osteocyte...

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Main Authors: McNulty, Melissa S., Bedell, Victoria M., Greenwood, Tammy M., Craig, Theodore A., Ekker, Stephen C., Kumar, Rajiv
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3435489/
https://ncbi.nlm.nih.gov/pubmed/22575304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gep.2012.04.003
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