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Reverse Phase Protein Array Profiling Reveals Distinct Proteomic Signatures Associated With Chronic Myeloid Leukemia Progression and With Chronic Phase in the CD34-Positive Compartment
BACKGROUND: Chronic myeloid leukemia (CML) is a clonal stem cell malignancy whose pathogenesis is driven by constitutive activation of the breakpoint cluster region–v-abl Abelson murine leukemia viral oncogene homolog 1 (BCR-ABL1) kinase. Although BCR-ABL1 activation is present in all patients with...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3435477/ https://ncbi.nlm.nih.gov/pubmed/22517119 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.27568 |
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