Reverse Phase Protein Array Profiling Reveals Distinct Proteomic Signatures Associated With Chronic Myeloid Leukemia Progression and With Chronic Phase in the CD34-Positive Compartment

BACKGROUND: Chronic myeloid leukemia (CML) is a clonal stem cell malignancy whose pathogenesis is driven by constitutive activation of the breakpoint cluster region–v-abl Abelson murine leukemia viral oncogene homolog 1 (BCR-ABL1) kinase. Although BCR-ABL1 activation is present in all patients with...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Quintás-Cardama, Alfonso, Qiu, Yi Hua, Post, Sean M., Zhang, Yiqun, Creighton, Chad J., Cortes, Jorge, Kornblau, Steven M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2012
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3435477/
https://ncbi.nlm.nih.gov/pubmed/22517119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.27568
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