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Application of base-catalysed reaction to the synthesis of dinucleotides containing the four common deoxyribonucleosides and of oligodeoxythymidylates.

The phosphorylation of nucleosides by a nucleoside phosphorofluoridate in the presence of potassium tert-butoxide is a very effective reaction for internucleotide bond synthesis in the case of pyrimidine deoxynucleosides. However, for the purine deoxynucleosides, yields are reduced due to competing...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: von Tigerstrom, R, Jahnke, P, Wylie, V, Smith, M
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1975
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC343541/
https://ncbi.nlm.nih.gov/pubmed/1187343
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