Homology Modeling of Dopamine D(2) and D(3) Receptors: Molecular Dynamics Refinement and Docking Evaluation

Dopamine (DA) receptors, a class of G-protein coupled receptors (GPCRs), have been targeted for drug development for the treatment of neurological, psychiatric and ocular disorders. The lack of structural information about GPCRs and their ligand complexes has prompted the development of homology mod...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Platania, Chiara Bianca Maria, Salomone, Salvatore, Leggio, Gian Marco, Drago, Filippo, Bucolo, Claudio
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2012
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3435408/
https://ncbi.nlm.nih.gov/pubmed/22970199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0044316
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