Homology Modeling of Dopamine D(2) and D(3) Receptors: Molecular Dynamics Refinement and Docking Evaluation

Dopamine (DA) receptors, a class of G-protein coupled receptors (GPCRs), have been targeted for drug development for the treatment of neurological, psychiatric and ocular disorders. The lack of structural information about GPCRs and their ligand complexes has prompted the development of homology mod...

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Main Authors: Platania, Chiara Bianca Maria, Salomone, Salvatore, Leggio, Gian Marco, Drago, Filippo, Bucolo, Claudio
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3435408/
https://ncbi.nlm.nih.gov/pubmed/22970199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0044316
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