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Phototriggerable 2′,7-Caged Paclitaxel

Three different variants of photoactivatable caged paclitaxel (PTX) have been synthesized and their bioactivity was characterized in in vitro assays and in living cells. The caged PTXs contain the photoremovable chromophore 4,5-dimethoxy-2-nitrobenzyloxycarbonyl (Nvoc) attached to position C7, C2�...

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Bibliografiske detaljer
Main Authors: Gropeanu, Radu A., Baumann, Hella, Ritz, Sandra, Mailänder, Volker, Surrey, Thomas, del Campo, Aránzazu
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3435387/
https://ncbi.nlm.nih.gov/pubmed/22970137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043657
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