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Phototriggerable 2′,7-Caged Paclitaxel

Three different variants of photoactivatable caged paclitaxel (PTX) have been synthesized and their bioactivity was characterized in in vitro assays and in living cells. The caged PTXs contain the photoremovable chromophore 4,5-dimethoxy-2-nitrobenzyloxycarbonyl (Nvoc) attached to position C7, C2�...

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Détails bibliographiques
Auteurs principaux: Gropeanu, Radu A., Baumann, Hella, Ritz, Sandra, Mailänder, Volker, Surrey, Thomas, del Campo, Aránzazu
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3435387/
https://ncbi.nlm.nih.gov/pubmed/22970137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043657
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