In Vitro and In Vivo Studies of the Trypanocidal Activity of Four Terpenoid Derivatives against Trypanosoma cruzi

Four terpenoid derivatives were examined for their activity against Trypanosoma cruzi. Our results show that two compounds were very active in vitro against both extra- and intracellular forms. These compounds, non-toxic for the host cells, are more effective than the reference drug benznidazole. Th...

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Detalhes bibliográficos
Main Authors: Ramírez-Macías, Inmaculada, Marín, Clotilde, Chahboun, Rachid, Messouri, Ibtissam, Olmo, Francisco, Rosales, María José, Gutierrez-Sánchez, Ramón, Alvarez-Manzaneda, Enrique, Sánchez-Moreno, Manuel
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Tropical Medicine and Hygiene 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3435351/
https://ncbi.nlm.nih.gov/pubmed/22802442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4269/ajtmh.2012.11-0471
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