Genomic DNA Copy-Number Alterations of the let-7 Family in Human Cancers

In human cancer, expression of the let-7 family is significantly reduced, and this is associated with shorter survival times in patients. However, the mechanisms leading to let-7 downregulation in cancer are still largely unclear. Since an alteration in copy-number is one of the causes of gene dereg...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Wang, Yanling, Hu, Xiaowen, Greshock, Joel, Shen, Liang, Yang, Xiaojun, Shao, Zhongjun, Liang, Shun, Tanyi, Janos L., Sood, Anil K., Zhang, Lin
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Public Library of Science 2012
Θέματα:
Research Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3435307/
https://ncbi.nlm.nih.gov/pubmed/22970210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0044399
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