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Copy-number-variation and copy-number-alteration region detection by cumulative plots

BACKGROUND: Regions with copy number variations (in germline cells) or copy number alteration (in somatic cells) are of great interest for human disease gene mapping and cancer studies. They represent a new type of mutation and are larger-scaled than the single nucleotide polymorphisms. Using genoty...

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Hlavní autoři: Li, Wentian, Lee, Annette, Gregersen, Peter K
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2648736/
https://ncbi.nlm.nih.gov/pubmed/19208171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-10-S1-S67
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